diff -r 9cb53c505acd -r 4f45c682eab0 src/hotspot/share/runtime/javaCalls.cpp
--- a/src/hotspot/share/runtime/javaCalls.cpp	Thu Nov 22 09:55:44 2018 +0100
+++ b/src/hotspot/share/runtime/javaCalls.cpp	Thu Nov 22 10:01:38 2018 +0100
@@ -427,7 +427,7 @@
 
 #if INCLUDE_JVMCI
   if (alternative_target != NULL) {
-    if (alternative_target->is_alive()) {
+    if (alternative_target->is_alive() && !alternative_target->is_unloading()) {
       thread->set_jvmci_alternate_call_target(alternative_target->verified_entry_point());
       entry_point = method->adapter()->get_i2c_entry();
     } else {